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Indeed, treatment with the VEGF inhibitor or deletion of VEGF receptor 1 (Vegfr-1) in mice results in impaired hepatocyte proliferation after APAP hepatotoxicity, and treatment with recombinant VEGF results in increased hepatocyte proliferation following APAP hepatotoxicity [5,40,41]

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If these reserves are insufficient, the pigeon may begin the race in excellent condition but struggle to maintain its pace during the later stages of the journey

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